- Frost N
- Weinborn M
- Gignac G
- Rainey-Smith SR
- Markovic S
- Gordon N
in Cognitively Normal Older Adults.
Am J Geriatr Psychiatr.
conducted a modest-sized randomized controlled trial (RCT; n=99) examining the effects
of 6-months of high-intensity vs. moderate-intensity aerobic exercise (AE) training
vs. an inactive control condition on several subdomains of executive function (EF;
set-shifting, working memory, inhibition, verbal generativity, and visual reasoning)
in cognitively unimpaired older adults. The study also examined the long-term effects
of AE training on EF 12-months after completion of the intervention. The intervention
had high adherence rates in both AE groups (mean >= 85%) and both AE groups showed
greater improvement in cardiorespiratory fitness over 6-months relative to the inactive
control condition. The primary study analyses revealed null results, such that no
differences were observed between the high-intensity AE, moderate-intensity AE, and
inactive control group for change in EF measures over the course of the 6-month intervention
or the 12-month follow-up period. As such, the study results did not support the hypothesis
that higher intensity of AE training would result in greater EF benefits. However,
it is likely the study was underpowered to detect these effects given the 3-group
intervention design in a modest-sized sample.
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